منابع مشابه
Identification of potent and selective neuropeptide Y Y(1) receptor agonists with orexigenic activity in vivo.
Neuropeptide Y (NPY) binds to a family of G-protein coupled receptors termed Y(1), Y(2), Y(3), Y(4), Y(5), and y(6). The use of various receptor subtype-selective agonists and antagonists has facilitated identification of the receptor subtypes responsible for mediating many of the biological effects of NPY. For example, the potent orexigenic activity of NPY is believed to be mediated by both th...
متن کاملAdenovirus-mediated suppression of HMGI(Y) protein synthesis as potential therapy of human malignant neoplasias.
High mobility group I (HMGI) proteins are overexpressed in several human malignant tumors. We previously demonstrated that inhibition of HMGI synthesis prevents thyroid cell transformation. Here, we report that an adenovirus carrying the HMGI(Y) gene in an antisense orientation (Ad-Yas) induced programmed cell death of two human thyroid anaplastic carcinoma cell lines (ARO and FB-1), but not no...
متن کاملDetermination of high mobility group I(Y) expression level in colorectal neoplasias: a potential diagnostic marker.
High mobility group I(Y) [HMGI(Y)] proteins are architectural factors abundantly expressed during embryogenesis, and their overexpression is known to be closely associated with neoplastic transformation of cells. This study was performed to investigate whether determination of HMGI(Y) expression level could assist in (a) differential diagnosis between colorectal carcinoma, adenoma, and normal t...
متن کاملKidney Donor Profile Index: Can it be extrapolated to our enviroment?
Es frecuente que nos encontremos ante el dilema de aceptar o no un riñón aparentemente no óptimo en un paciente que lleva un determinado tiempo en diálisis y desea ser trasplantado. La evaluación de la «calidad» del riñón sigue siendo muy controvertida. El concepto más simple es la edad. La edad del donante es un factor que limita la supervivencia del riñón y, aunque sabemos que, a mayor edad, ...
متن کاملPercutaneous Nephrostomy in Urogenital Neoplasias
Introduction: Urogenital neoplasias frequently progress with obstructive uropathy due to local spreading or pelvic metastases. The urinary obstruction must be immediately relieved in order to avoid deterioration in these patients. The percutaneous nephrostomy is a safe and effective method for relief the obstruction; however the indications of such procedures have been questioned in patients wi...
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ژورنال
عنوان ژورنال: Revista Mexicana de Trasplantes
سال: 2020
ISSN: 2007-6800
DOI: 10.35366/93488